Richter syndrome
نویسندگان
چکیده
منابع مشابه
Periorbital Richter Syndrome
Figure 1. Richter syndrome affecting eyelids on the left side in our patient.
متن کاملHow we treat Richter syndrome.
Richter syndrome (RS) is defined as the transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, most commonly diffuse large B-cell lymphoma (DLBCL). RS occurs in approximately 2% to 10% of CLL patients during the course of their disease, with a transformation rate of 0.5% to 1% per year. A combination of germline genetic characteristics, clinical features (eg, advanced...
متن کاملThe efficacy of ibrutinib in the treatment of Richter syndrome.
Contribution: S.W., E.S., C.D.C., and I.B. performed experiments; C.A., S.A., and F.O.H. provided clinical data and clinical care for patient P1; H.P., N.M.-D., E.F.-W., S.M., W.-D.H., and W.H. provided clinical data and clinical care for P2; T.L. performed chimerism analysis on blood samples from P1; K.B. conceived the study and provided laboratory resources; K.B., S.W., E.S., and I.B. planned...
متن کاملIbrutinib and rituximab induced rapid response in refractory Richter syndrome
We report a 53-year-old man diagnosed with Richter syndrome. He was heavily pretreated and was refractory to prior therapy. He received rituximab and ibrutinib, and achieved a significant response after 1 month of therapy. Our case illustrates the importance of investigation of rituximab and ibrutinib in Richter's syndrome.
متن کاملHodgkin's lymphoma as a unique variant of Richter syndrome.
progression in lymphadenopathy, the appearance/worsening of “B” symptoms, and elevated levels of lactate dehydrogenase, as well as histological features requiring a new tissue biopsy. The incidence of Richter syndrome in patients with CLL is 2% to 9%. Most frequently, CLL transforms into diffuse large B cell lymphoma, while in only 0.4% of patients will CLL transform to Hodgkin’s lymphoma [4]. ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2005
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.20773